Course Info for CHE242 - Organic Chem II

 This course is the second semester of a two-semester sequence of basic organic chemistry covering aromatic reactions, the chemistry of functional groups: alcohols and thiols, ethers, epoxides and sulfides, aldehydes and ketones, carboxylic acids, amines, and some biological compounds.  There are three hours of lecture and one two-hour laboratory per week.

PREREQUISITE: 

CHE241 - Organic Chemistry I or its equivalent

 REQUIRED TEXTBOOK:
  1. Organic Chemistry, 8th edition; Solomons and Fryle. John Wiley & Sons, Inc.

ISBN# 0-471-41799-8. 

  1. Study Guide and Solution Manual Organic Chemistry, 8th edition; Solomons and Fryle. John Wiley & Sons, Inc.

            ISBN# 0-471-21507-4. 

 REQUIRED MATERIALS:  

Safety glasses are required for all on-campus sections.

 As the result of instructional activities, students will be able to:

  1. recognize electrophilic (the usual mechanism) and nucleophilic substitution reactions of aromatic compounds.
  2. recognize alcohol and thiol functional groups, be able to name simple alcohols and thiols, know the properties, reactions and spectroscopic properties of these compounds.
  3. recognize ethers, epoxides and sulfides, be able to name ethers and know how to prepare ethers and reactions of ethers and epoxides, recognize the spectroscopic properties of ethers.
  4. recognize carbonyl compounds and their general reactions.
  5. recognize the aldehyde and ketone functional groups, be able to name simple aldehydes and ketones, will know general mechanism of nucleophilic additions to these compounds and know the general spectroscopic properties of aldehydes and ketones.
  6. recognize carboxylic acids, be able to name simple carboxylic acids, learn the preparation and reactions of carboxylic acids, know the general spectroscopic properties of carboxylic acids.
  7. recognize and be able to name simple amines, learn the preparation and reactions of amines, know the general spectroscopic properties of amines.
  8. be introduced to the organic chemistry of biomolecules.

GENERAL TOPICS OUTLINE:

  1. Carbon Compounds and Chemical Bonds.
  2. Representative Carbon Compounds: Functional Groups, Intermolecular Forces, and Infrared (IR) Spectroscopy.
  3. An Introduction to Organic Reactions: Acids and Bases.
  4. Alkanes: Nomenclature, Conformational Analysis, and an Introduction to Synthesis.
  5. Stereochemistry: Chiral Molecules.
  6. Ionic Reactions - Nucleophilic Substitution and Elimination Reactions of Alkyl Halides.
  7. Alkenes and Alkynes I: Properties and Synthesis, Elimination Reactions of Alkyl Halides.
  8. Alkenes and Alkynes II: Addition Reactions.
  9. Nuclear Magnetic Resonance and Mass Spectrometry: Tools for Structure Determination.
  10. Radical Reactions.
  11. Alcohols and Ethers.
  12. Alcohols from Carbonyl Compounds. Oxidation-Reduction and Organometallic Compounds.
  13. Conjugated Unsaturated Systems.
  14. Aromatic Compounds.
  15. Reactions of Aromatic Compounds.
  16. Aldehydes and Ketones I: Nucleoph ilic Addition to the Carbonyl Group.
  17. Aldehydes and Ketones II: Aldol Reactions.
  18. Carboxylic Acids and Their Derivatives. Nucleophilic Addition-Elimination at the Acyl Carbon.
  19. Synthesis and Reactions of ß-Dicarbonyl Compounds: More Chemistry of Enolate Ions.
  20. Amines.
Feel free to contact a member of the Science Department or the Science Department Chair.



 

 

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