Course Info for BIO204 - Microbiology
This course is an introduction to the study of bacteria, viruses, and eukaryotic members of the microbial world with an emphasis on their relationship to health and disease. Course topics include microbial structure, growth and replication, metabolism, pathogenicity of microorganisms, and the control of microbial growth, biotechnology and environmental microbiology. The laboratory includes basic techniques, such as staining, aseptic technique, and methods of bacterial identification. There are three hours of lecture and one two-hour laboratory per week.
This course meets the SUNY General Education course requirements for natural sciences.
PREREQUISITE:
Successful completion of BIO 101 or acceptance into CCC Nursing Program or Permission of Instructor.
COREQUISITE:
ENG101 - English Composition or equivalent.
REQUIRED TEXTBOOK:
This course uses an Open Education Resource (OER) which is free. You can access the textbook at the following URL: https://openstax.org/details/books/microbiology .
Leboffe & Pierce (2011). A photographic atlas for microbiology lab. 4th Edition. Morton
ISBN: 089582-872-3 (recommended)
REQUIRED MATERIALS:
Quad ruled composition notebook.
Safety glasses are required for all on-campus sections.
As the result of instructional activities, students will:
- Demonstrate knowledge of the history of microbiology, and be able to describe the contributions of Hooke and VanLeeuwenhoek to the observation of cells and microbes, of Redi, Virchow, and Pasteur to the theory of biogenesis, the contributions of Pasteur and Koch to the germ theory of disease, the contribution of Jenner to immunization, of Flemming to the discovery of antibiotics, of Erlich to antimicrobial chemotherapy, and of Semmelweis and Lister to the prevention of the transmission of microbial disease..
- Demonstrate appropriate terminology related to structure, metabolism, replication, and pathogenicity of prokaryotic microorganisms, eukaryotic microorganisms, viruses, and prions.
- Describe a variety of physical and chemical methods used in the control of microbes, and what effects each method has on microbes.
- Describe the molecular structure of DNA and RNA.
- Describe DNA synthesis, transcription, translation and protein synthesis, and be able to define gene expression.
- Explain the ways that microbial mutation and recombination happen in nature, and relate these subjects to evolution and natural selection.
- Explain the tools and processes of recombinant DNA technology, including selection, mutation, restriction enzymes, vectors, and polymerase chain reactions. The student will also be able to describe several applications of rDNA technology.
- Describe the methods of transmission of microbial disease, and explain the role of microorganisms in human disease.
- Describe the mechanisms of innate (nonspecific) immunity, including the function and structure of barrier defenses, phagocytes and natural killer cells, inflammation, fever, and antimicrobial proteins.
- Describe the mechanisms of adaptive (specific) immunity, including the roles of T cells, B cells, plasma cells, antibodies and cytokines. The student will also be able to explain immunological memory.
- Explain applications of the human immune response, including vaccination and diagnostic techniques.
- Explain immune disorders, including hypersensitivities, immunodeficiencies and autoimmunity.
- Explain fundamental concepts of epidemiology and disease prevention.
- Explain various mechanisms of action of antimicrobial drugs, and the challenges posed by antimicrobial drug resistance.
- Explain representative microbial diseases, including routes of transmission, symptoms, and treatments.
- Describe the carbon cycle, the nitrogen cycle, the sulfur cycle, and the phosphorus cycle. The student will also be able to explain basic concepts related to bioremediation and solid waste management.
- Explain the roles of microorganisms in water quality, as well as relate basic concepts pertaining to water treatment and wastewater treatment.
- Explain the theories of evolution and natural selection.
LABORATORY OBJECTIVES:
As the result of laboratory activities, the student will:
- Problem solve using the process of scientific inquiry during laboratory experimentation, including formulation of a hypothesis, designing an experiment that tests that hypothesis, recording data and evaluating the results of an experiment to come to a conclusion about the hypothesis.
- Demonstrate the ability to perform aseptic technique.
- Demonstrate the ability to culture microbes in the laboratory.
- Demonstrate the ability to perform microbial isolation.
- Demonstrate the ability to perform basic staining techniques.
- Perform techniques of microbial identification, and explain morphology, staining characteristics, and metabolic tests.
- Explain and perform physical and chemical methods for control of microbes using heat, cold, radiation, filtration, antiseptics, disinfectants and antibiotics.
LAB ACTIVITIES:
A complete list of proposed laboratory activities must be submitted with the course syllabi.
SUNY GENERAL EDUCATION KNOWLEDGE AREA LEARNING OUTCOMES:
Students will demonstrate the ability to:
- understand the methods scientists use to explore natural phenomena, including:
- observation
- hypothesis development
- measurement and data collection
- experimentation
- evaluation of evidence
- employment of mathematical analysis
- apply scientific data, concepts and models in one of the natural sciences
GENERAL TOPICS OUTLINE:
- Cell Structure, Microbial Structure and Growth
- Biochemistry and Molecular Biology
- Infectious agents
- Immunology
- Disease control
- Epidemiology
- Biotechnology
- Environmental Microbiology